The metabolome differs from other omics studies in that the metabolites measured are the end products of gene and protein regulation, and they can directly characterize the physiological pathways and states of the aging process. Metabolomics has the potential to provide innovative insights into the biological processes and molecular mechanisms involved in aging.\

 

Advanced Metabolomics Technologies

Metabolites are the end products of metabolism, the levels of which are correlated with aging and age-related diseases. Metabolomics can provide information on the identification and quantification of metabolites in organisms, and as technology continues to advance and develop it has high potential to elucidate the aging process, to elucidate metabolite changes resulting from physiological processes of various intrinsic and extrinsic factors, and to serve as a systematic approach to study and understand the aging process.

The commonly used technological platforms currently available are,

• NMR spectroscopy
• LC-MS
• GC-MS