Avanafil

Avanafil is an erectile dysfunction drug that works by blocking the action of the enzyme phosphodiesterase type 5 (PDE5). This causes cGMP to increase in the penis, which helps to improve blood flow and achieve a hard erection. It also has a much faster onset of action than other PDE5 inhibitors, meaning it takes effect within 15-30 minutes after taking the pill.

Its effectiveness was demonstrated in a placebo-controlled clinical study of patients with mild to moderate erectile dysfunction and premature ejaculation (PE). The study involved 270 male patients who were randomly assigned to placebo, Super Avana, or avanafil 200 mg. The primary efficacy endpoint was the percentage of sexual attempts that resulted in a sustained erection sufficient for successful intercourse (SEP 3) compared with baseline. The results showed that avanafil significantly increased the proportion of sexual attempts that succeeded compared with placebo (LS mean change for avanafil 100 and 200 mg, P.001 vs placebo).

The FDA approved avanafil in April 2012 under the brand name STENDRA in the U.S. and under the trade name SPEDRA in Europe. VIVUS acquired global development and commercial rights to avanafil through a collaboration arrangement with Mitsubishi Tanabe Pharma Corporation in 2012.

Avanafil is not recommended for use by women, children, or those with liver or kidney disease. It should not be taken with nitrates, alpha-blockers, or any other drugs that affect blood flow to the penis. It can also lower your blood pressure and cause dizziness and fainting, so you should avoid alcohol while taking it. It is also important to tell your doctor about any health conditions you have, including heart problems and other medications you are taking.

Dapoxetine

Premature ejaculation is a common problem that can occur for many reasons. In some cases, it is due to anxiety, depression, or a medical condition. The good news is that this is a treatable condition. Various self-help techniques and medications can help improve the situation. However, if you are struggling with a severe case of PE, it is best to seek treatment from your doctor. He or she can recommend different approaches that may work for you, including taking an antidepressant. These drugs can cause a delay in ejaculation, and can also help you feel better about yourself.

One of the more effective treatments is to take Dapoxetine. It is an SSRI that works to inhibit serotonin reuptake and has the side effect of delaying ejaculation. It is often recommended to be taken “on demand” one to three hours before sex. The medication can be found online, but you should consult your physician before taking it.

The drug is safe and effective in several clinical trials. In addition, female partners report greater satisfaction with a man who takes this medicine. However, it should not be used as a substitute for counseling and other therapies. It is important to address any underlying issues that are causing PE and to make lifestyle changes.

While this medication has no known serious side effects, it can be dangerous if you have certain conditions. You should not take it if you have liver disease kidney problems, or eye or heart disease. Also, you should not take it if you are taking nitrates for chest pain. The combination of these drugs can lead to a dangerous drop in blood pressure.

Dosage

Extra Super Avana contains two powerful elements of ED medicines, namely avanafil and dapoxetine. Both are type 5 phosphodiesterase inhibitors. During sexual stimulation, nitric oxide is released in the penis and activates an enzyme known as magnificently. This enzyme raises chemical levels of cyclic guanosine monophosphate (cGMP). The increased cGMP relaxes blood vessels to the penis, fills the erectile cavernous body with blood, and promotes enough erections to sustain sex.

Avanafil, the active compound in this ED tablet, inhibits PDE5. This allows nitric oxide to be produced, and it increases blood flow to the penis. This medicine starts working in 15 minutes and lasts for up to 6 hours. It works faster than Viagra and is a safe choice for those with pre-existing health conditions.

The other component of this ED medication is Dapoxetine, which is a light antidepressant that increases the length of sexual intercourse. It also prevents PE or premature ejaculation. This is a prescription-only medicine. It can be taken before or after sex, as instructed by the doctor.

It is important to note that this ED pill must be taken with a glass of water, and not with fatty or oily foods. It is also advised to avoid alcohol because it can decrease its effectiveness.

It is important to read the patient information leaflet if available, and consult your pharmacist or doctor before taking this medication. The leaflet will give you a full list of the side effects and precautions of this medication. It will also tell you if this medication interacts with any other medications. These include erythromycin, rifampicin, verapamil, or diltiazem for high blood pressure, and nitrates for heart diseases such as nitroglycerin or glycerol trinitrate.

Side Effects

When taken according to the instructions, this medication can help enhance intimacy by reducing erectile dysfunction and premature ejaculation. The drug is a powerful PDE5 inhibitor that works fast to deliver results. It works by improving the levels of cGMP in the penile muscles and increasing their diameter. This causes an increase in blood flow to the p*nis, which helps to achieve a hard erection.

This erectile dysfunction treatment by Sunrise Remedies is composed of two active ingredients at once: Avanafil and Dapoxetine. These two substances are effective in fighting erectile dysfunction. Avanafil improves and prolongs sexual intercourse, while dapoxetine prevents premature ejaculation. This medication should be taken 30 minutes before sexual activity, and it is usually advised to take no more than one pill a day. The pill should also be taken on an empty stomach to ensure that it is absorbed fully.

It is not recommended for use in women or children, and should not be used by anyone with a history of heart disease or high blood pressure. Patients should avoid alcohol and fatty foods while taking this medicine, as these can reduce the effectiveness of the medication. It is important to follow the manufacturer's instructions when using this medication, as excessive or irregular dosages can have serious side effects.

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