Description
Ethylene glycol: A colorless, odorless, sweet-tasting liquid used as an antifreeze, solvent and synthetic raw material.
CAS No.
CAS No. 107-21-1
FIRST AID MEASURES
Description of first aid measures Protection of first-aiders:
First Aid responders should pay attention to self-protection and use the recommended protective clothing (chemical resistant gloves, splash protection). If potential for exposure exists refer to Section 8 for specific personal protective equipment.
Inhalation: Move person to fresh air and keep comfortable for breathing; consult a physician.
Skin contact: Immediately flush skin with water while removing contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Destroy contaminated leather items such as shoes, belts, and watchbands. Suitable emergency safety shower facility should be immediately available.
Eye contact: Flush eyes thoroughly with water for several minutes. Remove contact lenses after the initial 1-2 minutes and continue flushing for several additional minutes. If effects occur, consult a physician, preferably an ophthalmologist.
Ingestion: Do NOT induce vomiting. Seek medical attention immediately. If person is fully conscious give 1 cup or 8 ounces (240 ml) of water. If medical advice is delayed and if an adult has swallowed several ounces of chemical, then give 3-4 ounces (1/3-1/2 Cup) (90-120 ml) of hard liquor such as 80 proof whiskey. For children, give proportionally less liquor at a dose of 0.3 ounce (1 1/2 tsp.) (8 ml) liquor for each 10 pounds of body weight, or 2 ml per kg body weight [e.g., 1.2 ounce (2 1/3 tbsp.) for a 40 pound child or 36 ml for an 18 kg child].
Most important symptoms and effects, both acute and delayed:
Aside from the information found under Description of first aid measures (above) and Indication of immediate medical attention and special treatment needed (below), any additional important symptoms and effects are described in Section 11: Toxicology Information.
Indication of any immediate medical attention and special treatment needed
Notes to physician: Maintain adequate ventilation and oxygenation of the patient. If several ounces (60 - 100 ml) of ethylene glycol have been ingested, early administration of ethanol may counter the toxic effects (metabolic acidosis, renal damage). Consider hemodialysis or peritoneal dialysis & thiamine 100 mg plus pyridoxine 50 mg intravenously every 6 hours. If ethanol is used, a therapeutically effective blood concentration in the range of 100 - 150 mg/dl may be achieved by a rapid loading dose followed by a continuous intravenous infusion. Consult standard literature for details of treatment. 4-Methyl pyrazole (Antizol®) is an effective blocker of alcohol dehydrogenase and should be used in the treatment of ethylene glycol (EG), di- or triethylene glycol (DEG, TEG), ethylene glycol butyl ether (EGBE), or methanol intoxication if available. Fomepizole protocol (Brent, J.et al., New England Journal of Medicine, Feb.8, 2001, 344:6, p.4249): loading dose 15 mg/kg intravenously, follow by bolus dose of 10 mg/kg every 12 hours; after 48 hours, increase bolus dose to 15 mg/kg every 12 hours. Continue fomepizole until serum methanol, EG, DEG, TEG or EGBE are undetectable. The signs and symptoms of poisoning include anion gap metabolic acidosis, CNS depression, renal tubular injury, and possible late stage cranial nerve involvement. Respiratory symptoms, including pulmonary edema, may be delayed. Persons receiving significant exposure
should be observed 24-48 hours for signs of respiratory distress. In severe poisoning, respiratory support with mechanical ventilation and positive end expiratory pressure may be required. If burn is present, treat as any thermal burn, after decontamination. If lavage is performed, suggest endotracheal and/or esophageal control. Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.
HANDLING AND STORAGE
Precautions for safe handling: Do not swallow. Avoid contact with eyes. Wash thoroughly after handling. Spills of these organic materials on hot fibrous insulations may lead to lowering of the autoignition temperatures possibly resulting in spontaneous combustion. See Section 8, EXPOSURE CONTROLS AND PERSONAL PROTECTION.
Conditions for safe storage: Do not store in: Galvanized steel. Opened or unlabeled containers.
Store in the following material(s): Carbon steel. Stainless steel. Store in original unopened container. See Section 10 for more specific information. Additional storage and handling information on this product may be obtained by calling your sales or customer service contact.
Storage stability
Shelf life: Use within 60 Month
DISPOSAL CONSIDERATIONS
Disposal methods: DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/Provincial and local laws and regulations. Regulations may vary in different locations. Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator. AS YOUR SUPPLIER, WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Information. FOR UNUSED & UNCONTAMINATED PRODUCT, the preferred options include sending to a licensed, permitted: Recycler. Reclaimer. Incinerator or other thermal destruction device.
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