PVP can be used as a binder for tablets and granules, a solubilizer for injections. Stabilizer, dispersant for liquid preparations, coating film-forming agent and pigment dispersant, co-precipitant for poorly soluble drugs, and delay agent and lubricant for eye drops, etc.
PVP can be used as a binder for tablets and granules, a solubilizer for injections. Stabilizer, dispersant for liquid preparations, coating film-forming agent and pigment dispersant, co-precipitant for poorly soluble drugs, and delay agent and lubricant for eye drops, etc.
As a binder: Drug tablets should have a certain mechanical strength so that they will not break when subjected to inevitable impact and friction during production, transportation, packaging and sales. At the same time, they are also required to disintegrate quickly in the digestive tract and release drugs after taking them. PVP with strong solubility can fully meet the above requirements.
As a co-precipitant: Many drugs have good efficacy, but their bioavailability is reduced due to their low solubility in water. Using certain water-soluble carriers to co-precipitate with drugs can increase the dissolution rate of drugs, improve efficacy and reduce dosage. PVP is the best choice.
As a solubilizer or dispersion stabilizer: PVP can be used as a solubilizer or crystal growth inhibitor in injections.
As a coating film-forming agent: Adding PVP to the film coating can not only increase the adhesion of the coating to the drug base, but also increase the stability of the coating suspension due to its excellent dispersibility, avoiding the reaggregation and migration of pigments.
As an ophthalmic adjuvant: Adding a certain amount of PVP to eye drops can reduce the irritation of the drug to the eyes, increase the viscosity, prolong the action time of eye drops in the eyes, and can also serve as artificial tears.
Poly Vinyl Pyrrolidone Uses
Application
Polyvinylpyrrolidone, referred to as PVP, is a non-ionic water-soluble polymer compound. It is the most characteristic, most deeply studied and widely studied fine chemical variety among N-vinylamide polymers. At present, it has developed into three categories of non-ionic, cationic and anionic, three grades of industrial grade, pharmaceutical grade a... morePoly Vinyl Pyrrolidone Uses https://www.sunflowerpolymer.com/povidone-use/
Poly Vinyl Pyrrolidone Uses
Application
Polyvinylpyrrolidone, referred to as PVP, is a non-ionic water-soluble polymer compound. It is the most characteristic, most deeply studied and widely studied fine chemical variety among N-vinylamide polymers. At present, it has developed into three categories of non-ionic, cationic and anionic, three grades of industrial grade, pharmaceutical grade and food grade, and a series of homopolymers, copolymers, cross-linked polymers and molecular complexes with molecular weights ranging from thousands to more than one million. It is widely used in industries and scientific research departments around the world with its excellent and unique properties, and still publishes more than 200 papers each year to show its ascendant status and prospects for continued development.
Pharma
The excellent physiological compatibility of PVP has attracted the attention of the medical community since its launch. Today, PVP has become a major synthetic drug excipient and is widely used throughout the world. It is included in the pharmacopoeias of Europe, the United States, Russia, Japan, China and other countries, and is accepted by health administrative departments of almost all countries in the world.
Industrial
PVP is a high molecular surfactant. It has hydrophilic and lipophilic groups in its molecular structure and good bonding ability to the surface of solid particles, so it can change the state of the interface or solution. It can be used as a dispersant, stabilizer, emulsifier, thickener, leveling agent, particle size regulator, anti-reprecipitation agent, coagulant, cosolvent and detergent aid. It can be used in solid glue, coatings, pigments, water treatment membranes, etc.
Cosmetics
Povidone is used in moisturizers and creams for its film-forming properties, which help to lock in moisture and create a protective barrier on the skin.
Food & Beverage
PVP and insoluble PVP can be used as clarifiers and stabilizers for beer, wine, and juice in the brewing and beverage industries, and have been legally permitted to be used in production in 38 countries around the world. Low-alcohol wine brewed with plant materials such as barley, rice, hops, etc. is rich in a variety of protein polyphenols.
Water Treatment
PVP K series products have a good pore-forming effect. Nowadays, membrane separation sewage treatment and water purification technology has become the mainstream technology in this industry. K90, K85 and K30 in the PVP K series are widely used as pore-forming agents in the water treatment industry.
Oral Care
The complexing and dispersing abilities of PVP can increase the detergency of toothpaste. Colgate's patent shows that adding a small amount of PVP has a significant effect on the detergency of toothpaste.
Other Application
PVP can be used as a dispersant for lithium battery cathode materials and as porogen.
The global market for povidone iodine had a value of USD 143.4 million in 2021 and is projected to experience a compound annual growth rate (CAGR) of 7.8% during the forecast period. The growth i...
