What is Ion Exchange Chromatography Resins?
These products are complementary with each other and are solutions of all process steps (capture, intermediate purification, and polishing) in chromatography for purifications of a variety of substances from small peptides to large proteins and viral particles.
Uni Series IEX Resins
UniCM, UniSP, UniQ, UniDEAE, and UniMSP are designed for the IEX purification of small proteins, peptides, oligo nucleotides, and small molecule such as antibiotics. Their supports are highly crosslinked polymethacrylate beads of uniformed particle size. Uni IEX resins have good hydrophilicity and low non-specific adsorbability by surface modification. Their smaller pore size makes them more suitable for IEX purification of small biomolecules. All of these resins meet the reproducibility, extensibility, and reliability requirements of today's industrial biological processes.
- Characteristics
| Product Name | UniCM-30S | UniCM-50XS | UniSP-30S | UniSP- 50XS | UniQ-30S | UniQ-50XS | UniDEAE-30S | UniDEAE-50XS | UniMSP-30XS | UniMSP-50XS |
|---|---|---|---|---|---|---|---|---|---|---|
| Support Matrix | Monodisperse Highly Crosslinked Polymethacrylate Bead | |||||||||
| Particle Size (µm) | 36 | 55 | 36 | 55 | 36 | 55 | 36 | 55 | 33 | 52 |
| Pore Size (Å) | 500 | 300 | 500 | 300 | 500 | 300 | 500 | 300 | 300 | 300 |
| IEX Type | Weak Cation | Strong Cation | Strong Anion | Weak Anion | Strong Cation /HIC Mixed Mode |
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| Charged Group | -CH2COO- | -(CH2)3SO3- | -CH2N+(CH3)3 | -CH2CH2N(CH2CH3)2 | -(CH2)3SO3- | |||||
| Total Ionic Capacity (mmol/ml) | ~0.23 | ~0.23 | ~0.23 | ~0.25 | ~0.23 | ~0.25 | ~0.20 | ~0.20 | ~0.25 | ~0.20 |
| Dynamic Binding Capacity | ~60 mg/ml (Lys) | ~55 mg/ml (Lys) | ~60 mg/ml (Lys) | ~55 mg/ml (Lys) | / | / | / | / | ~70 mg/ml (Lys) | ~65 mg/ml (Lys) |
| Operating Pressure | < 0.8 MPa | < 0.5 MPa | < 0.8 MPa | < 0.5 MPa | < 0.8 MPa | < 0.5 MPa | < 0.8 MPa | < 0.5 MPa | < 0.8 MPa | < 0.5 MPa |
| pH Range | 2 - 12 | 2 - 12 | 2 - 12 | 2 - 12 | 2-12 |